Regencell Bioscience (RGC) had the highest return last year by a mid-cap US stock, returning 15,606.8%.
| ASSET | YEAR | % RETURN |
|---|---|---|
Regencell Bioscience (RGC) | 2025 | 15,606.81% |
QMMM Holdings Limited Ordinary Shares (QMMM) | 2025 | 9,155.81% |
Hycroft Mining (HYMC) | 2025 | 951.77% |
Palvella Therapeutics (PVLA) | 2025 | 801.55% |
Celcuity LLC (CELC) | 2025 | 654.46% |
AXT (AXTI) | 2025 | 636.49% |
Almonty Industries Inc Common Shares (ALM) | 2025 | 511.81% |
TMC the metals (TMC) | 2025 | 441.23% |
GRAIL, LLC (GRAL) | 2025 | 380.3% |
Cogent Biosciences (COGT) | 2025 | 349.62% |
Aura Minerals Inc Common Shares (AUGO) | 2025 | 346.23% |
Sibanye Gold Ltd ADR (SBSW) | 2025 | 317.9% |
Ondas (ONDS) | 2025 | 290.4% |
Praxis Precision Medicines (PRAX) | 2025 | 279.23% |
Centrus Energy (LEU) | 2025 | 259.54% |
Opendoor Technologies (OPEN) | 2025 | 258.77% |
nLIGHT (LASR) | 2025 | 253.2% |
Sellas Life Sciences (SLS) | 2025 | 249.07% |
Precigen (PGEN) | 2025 | 248.33% |
CommScope (VISN) | 2025 | 244.68% |
OceanaGold (OGC) | 2025 | 240.05% |
Oklo (OKLO) | 2025 | 238.01% |
Astronics (ATRO) | 2025 | 234.2% |
First Majestic Silver (AG) | 2025 | 228.59% |
MP Materials (MP) | 2025 | 218.74% |
Mid-cap stocks are treated as having a market cap between $2B and $10B.