best performing small cap stocks in last 3 months

Alto Neuroscience (ANRO) has had the highest return between September 18, 2025 and December 18, 2025 by a small-cap US stock, returning 393.7%.

ASSETDATE% RETURN
Alto Neuroscience (ANRO)
9/18/2025 - 12/18/2025
393.65%
Capricor Therapeutics (CAPR)
9/18/2025 - 12/18/2025
320.39%
AXT (AXTI)
9/18/2025 - 12/18/2025
245.93%
Ventyx Biosciences (VTYX)
9/18/2025 - 12/18/2025
229.36%
Inhibrx Biosciences (INBX)
9/18/2025 - 12/18/2025
218.36%
Resolute Holdings Management (RHLD)
9/18/2025 - 12/18/2025
208.25%
MBX Biosciences, Inc Common Stock (MBX)
9/18/2025 - 12/18/2025
186.7%
Kodiak Sciences (KOD)
9/18/2025 - 12/18/2025
186.12%
PepGen (PEPG)
9/18/2025 - 12/18/2025
173.68%
Immix Biopharma (IMMX)
9/18/2025 - 12/18/2025
173.21%
Forge Global (FRGE)
9/18/2025 - 12/18/2025
172.96%
Relmada Therapeutics (RLMD)
9/18/2025 - 12/18/2025
171.24%
Alumis (ALMS)
9/18/2025 - 12/18/2025
167.15%
Northern Dynasty Minerals (NAK)
9/18/2025 - 12/18/2025
163.41%
Lyell Immunopharma (LYEL)
9/18/2025 - 12/18/2025
160.71%
NovaBay Pharmaceuticals (NBY)
9/18/2025 - 12/18/2025
156.48%
Ironwood Pharmaceuticals (IRWD)
9/18/2025 - 12/18/2025
154.69%
Hycroft Mining (HYMC)
9/18/2025 - 12/18/2025
152.63%
Monte Rosa Therapeutics (GLUE)
9/18/2025 - 12/18/2025
146.96%
BioAge Labs (BIOA)
9/18/2025 - 12/18/2025
143.7%
AnaptysBio (ANAB)
9/18/2025 - 12/18/2025
139.81%
Sight Sciences (SGHT)
9/18/2025 - 12/18/2025
138.73%
Replimune (REPL)
9/18/2025 - 12/18/2025
135.19%
Hotel101 Global Holdings Corp Class A Ordinary Shares (HBNB)
9/18/2025 - 12/18/2025
130.23%
DBV Technologies (DBVT)
9/18/2025 - 12/18/2025
123.47%
Small-cap stocks are treated as having a market cap between $300M and $2B.