Strive Asset Management (ASST) had the highest return in May 2025 by a small-cap US stock, returning 1,082.5%.

ASSET	MONTH	% RETURN
Strive Asset Management (ASST)	May 2025	1,082.52%
Roboai (AIIO)	May 2025	283.46%
CytomX Therapeutics (CTMX)	May 2025	258.11%
LZ Technology Holdings Limited Class B Ordinary Shares (LZMH)	May 2025	169.31%
Aeva Technologies, Inc Common Stock (AEVA)	May 2025	155.88%
LiveWire (LVWR)	May 2025	138.1%
Relmada Therapeutics (RLMD)	May 2025	134.38%
ADC Therapeutics (ADCT)	May 2025	116.08%
Flotek Industries (FTK)	May 2025	109.57%
OPAL Fuels (OPAL)	May 2025	105.2%
ProFrac (ACDC)	May 2025	101.45%
nLIGHT (LASR)	May 2025	93.97%
Serve Robotics Inc Common Stock (SERV)	May 2025	86.31%
Microvast (MVST)	May 2025	81.31%
Fulcrum Therapeutics (FULC)	May 2025	79.04%
DeFi Development (DFDV)	May 2025	75.12%
Claritev (CTEV)	May 2025	71.81%
Smart Digital Group Limited Ordinary Shares (SDM)	May 2025	69.75%
Domo (DOMO)	May 2025	68.21%
Meihua International Medical Technologies (MHUA)	May 2025	67.9%
Tango Therapeutics (TNGX)	May 2025	66.92%
Power Solutions International, Inc Common Stock (PSIX)	May 2025	66.81%
Strattec Security (STRT)	May 2025	65.87%
Village Farms International (VFF)	May 2025	65.28%
Lightbridge (LTBR)	May 2025	64.84%

Small-cap stocks are treated as having a market cap between $300M and $2B.