Indivior PLC Ordinary Shares (INDV) had the highest return in October 2022 by a small-cap US stock, returning 562%.

ASSET	MONTH	% RETURN
Indivior PLC Ordinary Shares (INDV)	October 2022	562%
Spyre Therapeutics (SYRE)	October 2022	94.34%
Enliven Therapeutics (ELVN)	October 2022	92.21%
Helix Energy Solutions (HLX)	October 2022	71.99%
ADEIA (ADEA)	October 2022	68.12%
Oceaneering International (OII)	October 2022	66.15%
89bio (ETNB)	October 2022	63.25%
Nabors Industries (NBR)	October 2022	60.65%
Advantage Solutions (ADV)	October 2022	57.21%
KULR Technology (KULR)	October 2022	51.85%
RPC (RES)	October 2022	51.43%
Tidewater (TDW)	October 2022	50.67%
Calumet Specialty Products Partners (CLMT)	October 2022	48.47%
Tilray (TLRY)	October 2022	45.88%
Riley Exploration Permian (REPX)	October 2022	45.71%
Byrna Technologies (BYRN)	October 2022	45.47%
Ardmore Shpng (ASC)	October 2022	44.4%
Entrada Therapeutics (TRDA)	October 2022	43.97%
Pacific Biosciences of California (PACB)	October 2022	43.05%
Greenbrier Companies (GBX)	October 2022	42.84%
Seadrill (SDRL)	October 2022	42.53%
CommScope (COMM)	October 2022	41%
Expro (XPRO)	October 2022	39.91%
Solaris Energy Infrastructure (SEI)	October 2022	39.84%
Monarch Casino & Resort (MCRI)	October 2022	39.63%

Small-cap stocks are treated as having a market cap between $300M and $2B.