QXO (QXO) had the highest return between 2011 and 2025 by a US stock, returning 4,822,400%.

ASSET	YEARS	% RETURN
QXO (QXO)	2011-2025	4,822,400%
Nutex Health (NUTX)	2011-2025	1,097,366.67%
Mingteng International Corporation Inc Ordinary Shares (MTEN)	2011-2025	954,185.71%
Integra Resources (ITRG)	2011-2025	801,900%
KULR Technology (KULR)	2011-2025	739,900%
Everbright Digital Holding Limited Ordinary Shares (EDHL)	2011-2025	599,900%
Blackboxstocks (BLBX)	2011-2025	476,076.47%
Xpel (XPEL)	2011-2025	277,177.78%
Immatics (IMTX)	2011-2025	209,900%
DevvStream Corp Common Stock (DEVS)	2011-2025	136,900%
MDxHealth SA ADR (MDXH)	2011-2025	108,081.82%
BioNexus Gene Lab Corp Common stock (BGLC)	2011-2025	96,241.46%
Aurora Cannabis (ACB)	2011-2025	56,166.67%
Sequans Communications (SQNS)	2011-2025	53,996.39%
NVIDIA (NVDA)	2011-2025	52,331.82%
MKDWELL Tech Inc Ordinary Share (MKDW)	2011-2025	42,757.14%
Cementos Pacasmayo SAA ADR (CPAC)	2011-2025	34,866.44%
Celsius (CELH)	2011-2025	29,736.92%
Iqstel (IQST)	2011-2025	29,293.94%
Alarum Technologies (ALAR)	2011-2025	25,209.73%
Tesla (TSLA)	2011-2025	25,033.85%
OrganiGram (OGI)	2011-2025	22,005.26%
Broadcom (AVGO)	2011-2025	16,735.3%
AquaBounty Technologies (AQB)	2011-2025	12,816.67%
Axon Enterprise (AXON)	2011-2025	11,856.42%