Azitra (AZTR) had the highest return between 2016 and 2023 by a US stock, returning 3,285,614.3%.

ASSET	YEARS	% RETURN
Azitra (AZTR)	2016-2023	3,285,614.29%
Fubotv (FUBO)	2016-2023	2,935,284.62%
MKDWELL Tech Inc Ordinary Share (MKDW)	2016-2023	2,812,400%
Advantage Solutions (ADV)	2016-2023	572,684.81%
KULR Technology (KULR)	2016-2023	379,900%
Agape ATP Corporation Common Stock (ATPC)	2016-2023	212,900%
Integra Resources (ITRG)	2016-2023	211,900%
Immatics (IMTX)	2016-2023	210,500%
BioNexus Gene Lab Corp Common stock (BGLC)	2016-2023	129,168.29%
Iqstel (IQST)	2016-2023	99,894.92%
MDxHealth SA ADR (MDXH)	2016-2023	93,709.52%
Lottery (SEGG)	2016-2023	55,432.79%
Heart Test Laboratories Inc Common Stock (HSCS)	2016-2023	50,194.12%
Zhongchao (ZCMD)	2016-2023	48,064.67%
AquaBounty Technologies (AQB)	2016-2023	39,483.33%
Amerant Bancorp (AMTB)	2016-2023	34,116.5%
Alarum Technologies (ALAR)	2016-2023	22,790.86%
Guardforce AI (GFAI)	2016-2023	15,861.54%
MMTEC (MTC)	2016-2023	15,617.09%
Aura Minerals Inc Common Shares (AUGO)	2016-2023	11,860.15%
ImmunoPrecise Antibodies (HYFT)	2016-2023	11,300%
Castellum (CTM)	2016-2023	10,937.04%
Connexa Sports Technologies (YYAI)	2016-2023	10,050%
DeFi Technologies (DEFT)	2016-2023	10,038%
Metalla Royalty & Streaming (MTA)	2016-2023	8,827.54%