best performing stocks in last 20 years with market cap above 50 billion

Natwest (NWG) has had the highest return between October 23, 2005 and October 23, 2025 by a US stock with a market cap of $50B+, returning 1,460,900%.

ASSETDATE% RETURN
Natwest (NWG)
10/23/2005 - 10/23/2025
1,460,900%
NVIDIA (NVDA)
10/23/2005 - 10/23/2025
73,125.02%
Tesla (TSLA)
10/23/2005 - 10/23/2025
34,554.61%
Netflix (NFLX)
10/23/2005 - 10/23/2025
29,410.96%
Broadcom (AVGO)
10/23/2005 - 10/23/2025
28,714.56%
Booking (BKNG)
10/23/2005 - 10/23/2025
25,973.81%
Mastercard (MA)
10/23/2005 - 10/23/2025
15,502.4%
Apple (AAPL)
10/23/2005 - 10/23/2025
15,482.42%
Transdigm (TDG)
10/23/2005 - 10/23/2025
15,081.71%
Axon Enterprise (AXON)
10/23/2005 - 10/23/2025
11,153.45%
MercadoLibre (MELI)
10/23/2005 - 10/23/2025
9,728.41%
Amazon (AMZN)
10/23/2005 - 10/23/2025
9,357.58%
Monster Beverage (MNST)
10/23/2005 - 10/23/2025
6,932.48%
Taiwan Semiconductor Manufacturing (TSM)
10/23/2005 - 10/23/2025
6,640.08%
Intuitive Surgical (ISRG)
10/23/2005 - 10/23/2025
6,637.62%
Regeneron Pharmaceuticals (REGN)
10/23/2005 - 10/23/2025
6,180.77%
ASML Holding NV ADR (ASML)
10/23/2005 - 10/23/2025
6,134.71%
Amphenol (APH)
10/23/2005 - 10/23/2025
5,811.78%
United Rentals (URI)
10/23/2005 - 10/23/2025
5,572.42%
O’Reilly Automotive (ORLY)
10/23/2005 - 10/23/2025
5,564.63%
AutoZone (AZO)
10/23/2005 - 10/23/2025
4,992.05%
Fortinet (FTNT)
10/23/2005 - 10/23/2025
4,880%
Lam Research (LRCX)
10/23/2005 - 10/23/2025
4,743.8%
NetEase (NTES)
10/23/2005 - 10/23/2025
4,644.94%
Chipotle Mexican Grill (CMG)
10/23/2005 - 10/23/2025
4,523.33%