Sitio Royalties (STR) had the highest return between 2015 and 2021 by a US stock, returning 14,529,700%.

ASSET	YEARS	% RETURN
Sitio Royalties (STR)	2015-2021	14,529,700%
P10 (PX)	2015-2021	13,419,700%
Amerant Bancorp (AMTB)	2015-2021	10,902,166.67%
Helport AI Limited Ordinary Shares (HPAI)	2015-2021	9,759,900%
BioNexus Gene Lab Corp Common stock (BGLC)	2015-2021	6,234,046.34%
JJill (JILL)	2015-2021	3,159,216.67%
Eastside Distilling (BLNE)	2015-2021	536,631.63%
Immatics (IMTX)	2015-2021	268,700%
Freedom (FRHC)	2015-2021	55,364%
Applied Digital (APLD)	2015-2021	43,095.88%
AquaBounty Technologies (AQB)	2015-2021	29,066.67%
Immunoprecise Antibodies (IPA)	2015-2021	27,387.18%
eXp World (EXPI)	2015-2021	22,769.31%
Alarum Technologies (ALAR)	2015-2021	20,843.95%
Avalon GloboCare (ALBT)	2015-2021	17,471.43%
Metalla Royalty & Streaming (MTA)	2015-2021	14,890.22%
Celsius (CELH)	2015-2021	14,811.04%
HIVE Blockchain Technologies (HIVE)	2015-2021	12,471.43%
Kaival Brands Innovations (KAVL)	2015-2021	12,321.67%
Sangoma Technologies (SANG)	2015-2021	6,644%
NVIDIA (NVDA)	2015-2021	5,977.33%
Blackboxstocks (BLBX)	2015-2021	5,850%
Zynex (ZYXI)	2015-2021	5,604.48%
Advanced Micro Devices (AMD)	2015-2021	5,229.63%
Shopify Inc Class A Subordinate Voting Shares (SHOP)	2015-2021	5,197.65%