Brera Holdings PLC Class B Ordinary Shares (BREA) had the highest return between 2020 and 2023 by a US stock, returning 1,311,900%.

ASSET	YEARS	% RETURN
Brera Holdings PLC Class B Ordinary Shares (BREA)	2020-2023	1,311,900%
NioCorp Developments Ltd Common Stock (NB)	2020-2023	531,566.67%
Azitra (AZTR)	2020-2023	492,757.14%
MDxHealth SA ADR (MDXH)	2020-2023	358,081.82%
Integra Resources (ITRG)	2020-2023	176,566.67%
BioNexus Gene Lab Corp Common stock (BGLC)	2020-2023	129,168.29%
ReShape Lifesciences (RSLS)	2020-2023	25,578.37%
MicroCloud Hologram (HOLO)	2020-2023	20,476.39%
Applied Digital (APLD)	2020-2023	15,501.85%
Foremost Lithium Resource & Technology Ltd Common stock (FMST)	2020-2023	7,452.87%
Alpha Metallurgical Resources (AMR)	2020-2023	3,862.45%
Celsius (CELH)	2020-2023	3,286.34%
JIN MEDICAL INTERNATIONAL LTD Ordinary Shares (ZJYL)	2020-2023	3,000.63%
Graf Industrial Corp Warrants (each warrant exercisable for one-half of one share of common stock each at an exercise price of $1150 per share) (GRAF.WT)	2020-2023	2,944.83%
Sigma Lithium Resources (SGML)	2020-2023	2,325.38%
CPI Card (PMTS)	2020-2023	2,032.22%
Atlas Lithium Corporation Common Stock (ATLX)	2020-2023	1,985.33%
Empire Petroleum (EP)	2020-2023	1,731.52%
Celldex Therapeutics (CLDX)	2020-2023	1,670.54%
374Water Inc Common Stock (SCWO)	2020-2023	1,477.78%
Hudson Technologies (HDSN)	2020-2023	1,290.15%
Riot Blockchain (RIOT)	2020-2023	1,257.02%
Aehr Test Systems (AEHR)	2020-2023	1,226.5%
Occidental Petroleum (OXY.WT)	2020-2023	1,184.82%
HIVE Blockchain Technologies (HIVE)	2020-2023	1,149.66%