Azitra (AZTR) had the highest return between 2020 and 2023 by a US stock, returning 3,285,614.3%.

ASSET	YEARS	% RETURN
Azitra (AZTR)	2020-2023	3,285,614.29%
MKDWELL Tech Inc Ordinary Share (MKDW)	2020-2023	2,812,400%
Applied Digital (APLD)	2020-2023	561,566.67%
MDxHealth SA ADR (MDXH)	2020-2023	358,081.82%
Agape ATP Corporation Common Stock (ATPC)	2020-2023	193,536.36%
Integra Resources (ITRG)	2020-2023	176,566.67%
authID (AUID)	2020-2023	147,712.5%
Heart Test Laboratories Inc Common Stock (HSCS)	2020-2023	50,194.12%
Zhongchao (ZCMD)	2020-2023	48,064.67%
Clean Energy Technologies, Inc Common Stock (CETY)	2020-2023	44,017.65%
XORTX Therapeutics (XRTX)	2020-2023	33,770.97%
INVO Fertility (IVF)	2020-2023	28,025%
Next Technology (NXTT)	2020-2023	21,837.32%
Guardforce AI (GFAI)	2020-2023	15,861.54%
Foremost Lithium Resource & Technology Ltd Common stock (FMST)	2020-2023	7,452.87%
Chord Energy (CHRD)	2020-2023	7,265.35%
Nukkleus (NUKK)	2020-2023	6,269.78%
Castellum (CTM)	2020-2023	5,318.18%
Prestige Wealth (AURE)	2020-2023	4,229.9%
Connexa Sports Technologies (YYAI)	2020-2023	3,960%
Alpha Metallurgical Resources (AMR)	2020-2023	3,862.45%
Celsius (CELH)	2020-2023	3,286.34%
JIN MEDICAL INTERNATIONAL LTD Ordinary Shares (ZJYL)	2020-2023	3,000.63%
COSCIENS Biopharma (CSCI)	2020-2023	2,700%
Sigma Lithium Resources (SGML)	2020-2023	2,325.38%