Diversified Energy (DEC) had the highest return between 2005 and 2023 by a US stock, returning 6,087,200%.

ASSET	YEARS	% RETURN
Diversified Energy (DEC)	2005-2023	6,087,200%
QXO (QXO)	2005-2023	4,385,826.92%
Cemtrex (CETX)	2005-2023	3,969,090.14%
Azitra (AZTR)	2005-2023	3,285,614.29%
Brera Holdings PLC Class B Ordinary Shares (BREA)	2005-2023	1,311,900%
Northern Oil & Gas (NOG)	2005-2023	1,301,207.69%
Sequans Communications (SQNS)	2005-2023	852,309.64%
GeoVax Labs (GOVX)	2005-2023	601,566.67%
Metalla Royalty & Streaming (MTA)	2005-2023	439,900%
MDxHealth SA ADR (MDXH)	2005-2023	437,677.78%
KULR Technology (KULR)	2005-2023	379,900%
Integra Resources (ITRG)	2005-2023	211,900%
Immatics (IMTX)	2005-2023	210,500%
Blackboxstocks (BLBX)	2005-2023	165,782.35%
Perspective Therapeutics (CATX)	2005-2023	133,233.33%
BioNexus Gene Lab Corp Common stock (BGLC)	2005-2023	129,168.29%
Universal Insurance (UVE)	2005-2023	90,283.83%
Next Technology (NXTT)	2005-2023	71,051.36%
Aurora Cannabis (ACB)	2005-2023	63,366.67%
Lottery (SEGG)	2005-2023	55,432.79%
Heart Test Laboratories Inc Common Stock (HSCS)	2005-2023	50,194.12%
Ring Energy (REI)	2005-2023	48,566.67%
India Globalization Capital (IGC)	2005-2023	46,566.67%
AquaBounty Technologies (AQB)	2005-2023	39,483.33%
Eastside Distilling (BLNE)	2005-2023	38,638.74%