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best stock gainer over the last year

Vyne Therapeutics (VYNE) has had the highest return since August 16, 2025 by a US stock, returning 780,669.2%.

ASSET% RETURN
Vyne Therapeutics (VYNE)
780,669.23%
Aptorum Group Ltd Class A (APM)
600,614.29%
WhiteHawk Minerals (WHK)
435,733.33%
SharonAI Holdings, Inc Class A Common Stock (SHAZ)
382,250%
Seaport Therapeutics, Inc Common Stock (SPTX)
242,100%
QMMM Holdings Limited Ordinary Shares (QMMM)
4,164.29%
AXT (AXTI)
3,863.11%
Sandisk (SNDK)
3,608.72%
Mega Fortune Company Limited Ordinary Shares (MGRT)
3,077.14%
CBL International Limited Ordinary Shares (BANL)
1,550.81%
Erasca (ERAS)
1,101.31%
New Era Energy & Digital (NUAI)
1,052.27%
Alto Neuroscience (ANRO)
946.91%
Damora Therapeutics (DMRA)
843.47%
Climb Bio (CLYM)
728.93%
Micron Technology (MU)
701.99%
Lumentum (LITE)
695.31%
Sellas Life Sciences (SLS)
679.27%
Praxis Precision Medicines  (PRAX)
677.8%
Q32 Bio (QTTB)
665.15%
Shattuck Labs  (STTK)
657.14%
Zenta (ZTG)
655.38%
Adlai Nortye Ltd American Depositary Shares (ANL)
652.84%
Relmada Therapeutics (RLMD)
642.92%
Trinity Biotech (TRIB)
633.5%

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