
Seaport Therapeutics, Inc Common Stock (SPTX) has had the highest return since January 1, 2026 by a US stock, returning 168,000%.
| ASSET | % RETURN |
|---|---|
Seaport Therapeutics, Inc Common Stock (SPTX) | 168,000% |
Reliance Global (RELI) | 96,561.49% |

| ASSET | % RETURN |
|---|---|
Seaport Therapeutics, Inc Common Stock (SPTX) | 168,000% |
Reliance Global (RELI) | 96,561.49% |