Amerant Bancorp (AMTB) had the highest return between 2018 and 2020 by a US stock, returning 4,788,066.7%.

ASSET	YEARS	% RETURN
Amerant Bancorp (AMTB)	2018-2020	4,788,066.67%
Avalon GloboCare (ALBT)	2018-2020	1,049,900%
Immatics (IMTX)	2018-2020	215,700%
Alarum Technologies (ALAR)	2018-2020	115,347.15%
Kaival Brands Innovations (KAVL)	2018-2020	85,899.92%
Nocera (NCRA)	2018-2020	8,717.64%
FitLife Brands, Inc Common Stock (FTLF)	2018-2020	8,526.2%
Enphase Energy (ENPH)	2018-2020	7,241.84%
Nuvve (NVVEW)	2018-2020	5,366.67%
Golden Matrix (GMGI)	2018-2020	4,493.33%
Tandem Diabetes Care (TNDM)	2018-2020	3,971.49%
Ryvyl (RVYL)	2018-2020	3,765.25%
Xpel (XPEL)	2018-2020	3,505.59%
Digital Turbine (APPS)	2018-2020	3,042.22%
Reliance Global (RELI)	2018-2020	2,900%
Integra Resources (ITRG)	2018-2020	2,548.65%
Osisko Development (ODV)	2018-2020	2,497.4%
Sobr Safe (SOBR)	2018-2020	2,297.17%
Graf Industrial Corp Warrants (each warrant exercisable for one-half of one share of common stock each at an exercise price of $1150 per share) (GRAF.WT)	2018-2020	2,208.78%
Arrowhead Pharmaceuticals (ARWR)	2018-2020	1,979.4%
Fusion Fuel Green (HTOOW)	2018-2020	1,747.22%
Quantum Computing (QUBT)	2018-2020	1,663.75%
Trade Desk (TTD)	2018-2020	1,653.12%
Ontrak (OTRK)	2018-2020	1,547.73%
Magnite (MGNI)	2018-2020	1,542.25%