PharmaCyte Biotech (PMCB) had the highest return in 2008 by a US stock, returning 27,947.6%.

ASSET	YEAR	% RETURN
PharmaCyte Biotech (PMCB)	2008	27,947.62%
Weatherford International (WFRD)	2008	7,300%
Oxley Bridge Acquisition Limited Class A Ordinary Shares (OBA)	2008	5,749.06%
TOMI Environmental Solutions (TOMZ)	2008	1,650%
LifeMD (LFMD)	2008	1,483.33%
INVO Fertility (IVF)	2008	1,275%
Quantum Computing (QUBT)	2008	1,250%
Versus Systems Inc. (VS)	2008	668%
374Water Inc Common Stock (SCWO)	2008	471.43%
Emergent Biosolutions (EBS)	2008	421.16%
Lineage Cell Therapeutics (LCTX)	2008	331.75%
Crawford (CRD.B)	2008	251.21%
Sanara Medtech (SMTI)	2008	231.68%
Mexco Energy (MXC)	2008	209.75%
Metalla Royalty & Streaming (MTA)	2008	171.43%
Duos Technologies (DUOT)	2008	160%
Ammo (POWW)	2008	150%
New Concept Energy (GBR)	2008	137.71%
Where Food Comes From (WFCF)	2008	114.29%
Axogen (AXGN)	2008	111.54%
NanoViricides (NNVC)	2008	107.69%
Intrusion (INTZ)	2008	94.44%
Trex (TREX)	2008	90.51%
Maywood Acquisition Corp Class A Ordinary Shares (MAYA)	2008	88.89%
Grand Canyon Education (LOPE)	2008	87.8%