Connexa Sports Technologies (YYAI) had the highest return between 2005 and 2021 by a US stock, returning 34,399,900%.

ASSET	YEARS	% RETURN
Connexa Sports Technologies (YYAI)	2005-2021	34,399,900%
Cemtrex (CETX)	2005-2021	22,737,576.06%
QXO (QXO)	2005-2021	9,433,866.67%
GeoVax Labs (GOVX)	2005-2021	7,144,636.84%
BioNexus Gene Lab Corp Common stock (BGLC)	2005-2021	6,234,046.34%
KULR Technology (KULR)	2005-2021	5,519,900%
Nutex Health (NUTX)	2005-2021	4,119,900%
Sequans Communications (SQNS)	2005-2021	1,427,610.84%
Eastside Distilling (BLNE)	2005-2021	1,074,975.08%
MDxHealth SA ADR (MDXH)	2005-2021	1,057,677.78%
Metalla Royalty & Streaming (MTA)	2005-2021	984,885.71%
Blackboxstocks (BLBX)	2005-2021	839,900%
Iqstel (IQST)	2005-2021	738,852.53%
Aurora Cannabis (ACB)	2005-2021	721,233.33%
AquaBounty Technologies (AQB)	2005-2021	583,233.33%
Future Fintech (FTFT)	2005-2021	472,368.92%
Integra Resources (ITRG)	2005-2021	429,900%
Immatics (IMTX)	2005-2021	268,700%
Guardforce AI (GFAI)	2005-2021	207,592.31%
India Globalization Capital (IGC)	2005-2021	163,233.33%
INVO Fertility (IVF)	2005-2021	149,750.01%
Perspective Therapeutics (CATX)	2005-2021	129,900%
Bone Biologics (BBLG)	2005-2021	123,529.26%
Processa Pharmaceuticals (PCSA)	2005-2021	116,566.67%
LM Funding America (LMFA)	2005-2021	98,081.82%