Charming Medical Limited Class A Ordinary Shares (MCTA) had the highest return in October 2025 by a US stock, returning 412%.

ASSET	MONTH	% RETURN
Charming Medical Limited Class A Ordinary Shares (MCTA)	October 2025	411.98%
New Era Energy & Digital (NUAIW)	October 2025	410.66%
Rani Therapeutics (RANI)	October 2025	358.33%
VisionWave Holdings, Inc Warrant (VWAVW)	October 2025	298.66%
Praxis Precision Medicines (PRAX)	October 2025	276.87%
Alto Neuroscience (ANRO)	October 2025	254.75%
Cambium Networks (CMBM)	October 2025	226.81%
Royalty Management (RMCOW)	October 2025	212.62%
OneMedNet (ONMDW)	October 2025	212.37%
Intensity Therapeutics, Inc Common stock (INTS)	October 2025	185.68%
IO Biotech (IOBT)	October 2025	184.46%
Solidion Technology (STI)	October 2025	175.6%
New Era Energy & Digital (NUAI)	October 2025	174.33%
ESS Tech (GWH)	October 2025	171.71%
Wisekey International (WKEY)	October 2025	168.99%
Mawson Infrastructure (MIGI)	October 2025	165.12%
Digi Power X (DGXX)	October 2025	162.17%
Ventyx Biosciences (VTYX)	October 2025	159.27%
Grupo Supervielle (SUPV)	October 2025	150.91%
Infrared Cameras (MSAI)	October 2025	144.9%
Inhibrx Biosciences (INBX)	October 2025	143.69%
Davis Commodities Limited Ordinary Shares (DTCK)	October 2025	142.86%
GSI Technology (GSIT)	October 2025	142.4%
rYojbaba Co, Ltd Common Shares (RYOJ)	October 2025	137.24%
Replimune (REPL)	October 2025	135.02%