MDxHealth SA ADR (MDXH) had the highest return in Q4 2021 by a US stock, returning 679,900%.

ASSET	QUARTER	% RETURN
MDxHealth SA ADR (MDXH)	Q4 2021	679,900%
Trump Media & Technology (DJTWW)	Q4 2021	2,769.57%
Vivid Seats (SEAT)	Q4 2021	2,119.68%
Synergy CHC Corp Common Stock (SNYR)	Q4 2021	991.67%
LakeShore Biopharma (LSB)	Q4 2021	898.24%
Huadi International (HUDI)	Q4 2021	614.03%
Imperial Petroleum (IMPP)	Q4 2021	434.93%
Trump Media & Technology (DJT)	Q4 2021	414.3%
Biofrontera Inc Warrants (BFRIW)	Q4 2021	407.04%
Nutriband Inc Warrant (NTRBW)	Q4 2021	291.27%
Cerberus Cyber Sentinel (CISO)	Q4 2021	282.35%
Oxbridge Re Holdings Equity Warrant (OXBRW)	Q4 2021	269.17%
Jowell Global (JWEL)	Q4 2021	265.63%
Longeveron LLC (LGVN)	Q4 2021	242.9%
Smith-Midland (SMID)	Q4 2021	241.57%
Arqit Quantum Inc Warrants (ARQQW)	Q4 2021	231.43%
Trio-Tech International (TRT)	Q4 2021	212.33%
Lendway (LDWY)	Q4 2021	207.73%
Dogness International Corp Class A (DOGZ)	Q4 2021	195.09%
Phunware (PHUN)	Q4 2021	184.32%
Reliance Global (RELI)	Q4 2021	174.04%
Iveda Solutions (IVDA)	Q4 2021	168.29%
TDH (PETZ)	Q4 2021	161.9%
Scisparc (SPRC)	Q4 2021	149.2%
Palladyne AI (PDYNW)	Q4 2021	144.58%