GeoVax Labs (GOVX) had the highest return between 2010 and 2010 by a US stock, returning 5,263,157,794.2%.

ASSET	YEARS	% RETURN
GeoVax Labs (GOVX)	2010-2010	5,263,157,794.21%
NextTrip (NTRP)	2010-2010	199,900%
Aris Mining (ARMN)	2010-2010	184,239.52%
BTCS (BTCS)	2010-2010	5,920.01%
ClearOne (CLRO)	2010-2010	1,720.75%
Intelligent Protection Management (IPM)	2010-2010	1,093.33%
Sunshine Biopharma (SBFM)	2010-2010	941.67%
Xcel Brands (XELB)	2010-2010	650%
Radcom (RDCM)	2010-2010	619.48%
Edesa Biotech (EDSA)	2010-2010	615%
Mitek Systems (MITK)	2010-2010	611.76%
Wabash National (WNC)	2010-2010	533.71%
Ammo (POWW)	2010-2010	500%
Amarin (AMRN)	2010-2010	473.43%
BOS Better Online Solutions (BOSC)	2010-2010	470.34%
IDT (IDT)	2010-2010	426.18%
LGL (LGL)	2010-2010	413.99%
Research Solutions (RSSS)	2010-2010	381.82%
Radiant Logistics (RLGT)	2010-2010	348.98%
Westwater Resources (WWR)	2010-2010	341.56%
Sow Good Inc Common Stock (SOWG)	2010-2010	320%
Novanta (NOVT)	2010-2010	314.9%
Flotek Industries (FTK)	2010-2010	306.72%
Versus Systems Inc. (VS)	2010-2010	302%
Avino Silver & Gold Mines (ASM)	2010-2010	297.14%