Sandisk (SNDK) has had the highest return between 2025 and 2026 by a mega-cap US stock, returning 4,135.5%.

ASSET	YEARS	% RETURN
Sandisk (SNDK)	2025-2026	4,135.45%
Micron Technology (MU)	2025-2026	1,004.96%
Intel (INTC)	2025-2026	355.22%
Lam Research (LRCX)	2025-2026	343.01%
Dell Technologies (DELL)	2025-2026	321%
Advanced Micro Devices (AMD)	2025-2026	289.79%
Banco Santander SA ADR (SAN)	2025-2026	238.29%
Applied Materials (AMAT)	2025-2026	197.27%
KLA (KLAC)	2025-2026	193.1%
GE Vernova LLC (GEV)	2025-2026	187.61%
Crowdstrike (CRWD)	2025-2026	163.14%
ASML Holding NV ADR (ASML)	2025-2026	149.53%
Palantir Technologies (PLTR)	2025-2026	144%
HSBC Holdings PLC ADR (HSBC)	2025-2026	131.02%
Caterpillar (CAT)	2025-2026	128.32%
Taiwan Semiconductor Manufacturing (TSM)	2025-2026	120.28%
Marvell Technology (MRVL)	2025-2026	119.22%
BHP (BHP)	2025-2026	108.07%
Palo Alto Networks (PANW)	2025-2026	107.51%
GE Aerospace (GE)	2025-2026	105.82%
Arm Holdings plc American Depositary Shares (ARM)	2025-2026	104.18%
Mitsubishi UFJ Financial Group Inc ADR (MUFG)	2025-2026	100.23%
Cisco Systems (CSCO)	2025-2026	96.93%
Citigroup (C)	2025-2026	95.12%
Johnson & Johnson (JNJ)	2025-2026	91.65%

Mega-cap stocks are treated as having a market cap of $200B+.