Integra Resources (ITRG) has had the highest return since 2017 by a US stock, returning 795,900%.

ASSET	% RETURN
Integra Resources (ITRG)	795,900%
KULR Technology (KULR)	707,400%
MDxHealth SA ADR (MDXH)	669,900%
SharonAI Holdings, Inc Class A Common Stock (SHAZ)	449,130.77%
Everbright Digital Holding Limited Ordinary Shares (EDHL)	259,900%
Immatics (IMTX)	196,700%
DevvStream Corp Common Stock (DEVS)	78,500%
BioNexus Gene Lab Corp Common stock (BGLC)	61,607.32%
Castellum (CTM)	50,089.47%
Applied Digital (APLD)	43,483.33%
Iqstel (IQST)	39,300%
Synergy CHC Corp Common Stock (SNYR)	33,150%
Amerant Bancorp (AMTB)	31,130.1%
TSS, Inc Common Stock (TSSI)	24,375%
MKDWELL Tech Inc Ordinary Share (MKDW)	21,715.18%
Alarum Technologies (ALAR)	19,310.03%
AquaBounty Technologies (AQB)	13,508.33%
FitLife Brands, Inc Common Stock (FTLF)	12,621.15%
Aura Minerals Inc Common Shares (AUGO)	9,073.2%
Mingteng International Corporation Inc Ordinary Shares (MTEN)	8,642.86%
MMTEC (MTC)	8,230.06%
Heart Test Laboratories Inc Common Stock (HSCS)	7,607.35%
Regencell Bioscience (RGC)	7,496.58%
NVIDIA (NVDA)	6,902.84%
Quantum Computing (QUBT)	6,341.67%