Monster Beverage (MNST) had the highest return between 2000 and 2009 by a US stock in the S&P 500 (GSPC), returning 7,074.9%.

ASSET	YEARS	% RETURN
Monster Beverage (MNST)	2000-2009	7,074.89%
Deckers Outdoor (DECK)	2000-2009	3,775.93%
Altria (MO)	2000-2009	2,468.3%
CarMax (KMX)	2000-2009	2,055.56%
Intuitive Surgical (ISRG)	2000-2009	1,585.8%
ANSYS (ANSS)	2000-2009	1,498.56%
Leidos (LDOS)	2000-2009	1,409.31%
NVR (NVR)	2000-2009	1,388.4%
BlackRock (BLK)	2000-2009	1,376.71%
Tapestry (TPR)	2000-2009	1,372.19%
Tractor Supply (TSCO)	2000-2009	1,218.78%
DaVita HealthCare Partners (DVA)	2000-2009	1,205.33%
Gilead Sciences (GILD)	2000-2009	1,111.94%
EOG Resources (EOG)	2000-2009	1,085.52%
Western Digital (WDC)	2000-2009	938.79%
Hologic (HOLX)	2000-2009	897.8%
Cognizant Technology Solutions Corp Class A (CTSH)	2000-2009	886.78%
JB Hunt Transport Services (JBHT)	2000-2009	875.8%
Occidental Petroleum (OXY)	2000-2009	873.08%
Old Dominion Freight Line (ODFL)	2000-2009	863.69%
CME (CME)	2000-2009	834.58%
Contura Energy (CTRA)	2000-2009	755.8%
Quest Diagnostics (DGX)	2000-2009	719.68%
Laboratory Corporation of America (LH)	2000-2009	711.84%
Apple (AAPL)	2000-2009	703.73%