Sila Realty Trust (SILA) has had the highest return since 2021 by a US stock, returning 6,094,900%.

ASSET	% RETURN
Sila Realty Trust (SILA)	6,094,900%
Brera Holdings PLC Class B Ordinary Shares (BREA)	5,039,900%
NioCorp Developments Ltd Common Stock (NB)	1,323,233.33%
MDxHealth SA ADR (MDXH)	437,172.73%
DevvStream Corp Common Stock (DEVS)	236,900%
BioNexus Gene Lab Corp Common stock (BGLC)	229,900%
Applied Digital (APLD)	70,646.67%
Diversified Energy (DEC)	50,267.65%
CID HoldCo, Inc Warrants (DAICW)	39,900%
ZTST (ZTST)	30,631.89%
Castellum (CTM)	24,218.18%
Wearable Devices (WLDSW)	16,476.27%
Azitra (AZTR)	14,042.86%
USA Rare Earth (USARW)	8,423.53%
Lottery (SEGG)	6,957.85%
HCM II Acquisition (HONDW)	5,804.76%
Regencell Bioscience (RGC)	5,314.82%
Foremost Lithium Resource & Technology Ltd Common stock (FMST)	3,987.79%
QMMM Holdings Limited Ordinary Shares (QMMM)	3,880%
Webull Corporation Warrants (BULLW)	3,172.22%
Diginex Limited Ordinary Shares (DGNX)	2,992.96%
Celestica (CLS)	2,767.12%
Power Solutions International, Inc Common Stock (PSIX)	2,756.97%
Nova Minerals Limited Warrant (NVAWW)	2,542%
TSS, Inc Common Stock (TSSI)	2,378.62%