East West Bancorp (EWBC) had the lowest return in June 2008 by a large-cap US stock, returning -46.9%.

ASSET	MONTH	% RETURN
East West Bancorp (EWBC)	June 2008	-46.88%
Fifth Third Bancorp (FITB)	June 2008	-44.34%
KeyCorp (KEY)	June 2008	-43.49%
United Airlines (UAL)	June 2008	-38.52%
American Airlines (AAL)	June 2008	-37.96%
Regions Financial (RF)	June 2008	-36.65%
Heico (HEI)	June 2008	-35.52%
Evercore Partners (EVR)	June 2008	-34.66%
Insmed (INSM)	June 2008	-34.17%
Huntington Bancshares (HBAN)	June 2008	-34%
HEICO (HEI.A)	June 2008	-32.11%
Las Vegas Sands (LVS)	June 2008	-31.23%
MGM Resorts International (MGM)	June 2008	-30.64%
Live Nation Entertainment (LYV)	June 2008	-30.17%
Ford Motor (F)	June 2008	-29.78%
Penske Automotive (PAG)	June 2008	-29.71%
Embraer SA ADR (ERJ)	June 2008	-29.14%
Comerica (CMA)	June 2008	-29.11%
Axon Enterprise (AXON)	June 2008	-28.71%
Webster Financial (WBS)	June 2008	-28.19%
Coca-Cola Consolidated (COKE)	June 2008	-28.14%
Dillard's (DDS)	June 2008	-28.13%
Bank of America (BAC)	June 2008	-28.08%
MercadoLibre (MELI)	June 2008	-27.54%
Truist Financial (TFC)	June 2008	-27.51%

Large-cap stocks are treated as having a market cap of $10B+.