Praxis Precision Medicines (PRAX) had the lowest return in March 2023 by a mid-cap US stock, returning -73.2%.

ASSET	MONTH	% RETURN
Praxis Precision Medicines (PRAX)	March 2023	-73.21%
Western Alliance Bancorporation (WAL)	March 2023	-51.61%
Nektar Therapeutics (NKTR)	March 2023	-50.5%
Intuitive Machines (LUNR)	March 2023	-45.23%
Ondas (ONDS)	March 2023	-41.62%
Zions Bancorporation (ZION)	March 2023	-40.45%
Customers Bancorp (CUBI)	March 2023	-39.83%
BankUnited (BKU)	March 2023	-35.74%
UMB Financial (UMBF)	March 2023	-35.74%
United Natural Foods (UNFI)	March 2023	-35.07%
Xometry (XMTR)	March 2023	-34.49%
Arcutis Biotherapeutics (ARQT)	March 2023	-33.57%
Amneal Pharmaceuticals, Inc Class A Common Stock (AMRX)	March 2023	-32.52%
Edgewise Therapeutics (EWTX)	March 2023	-31.02%
Maase (MAAS)	March 2023	-30.74%
CVB Financial (CVBF)	March 2023	-30.15%
Nextdecade (NEXT)	March 2023	-30%
Bank of Hawaii (BOH)	March 2023	-29.97%
Lincoln National (LNC)	March 2023	-29.96%
Spyre Therapeutics (SYRE)	March 2023	-29.61%
Columbia Banking System (COLB)	March 2023	-28.86%
Centrus Energy (LEU)	March 2023	-28.11%
Day One Biopharmaceuticals (DAWN)	March 2023	-27.92%
Banc of California (BANC)	March 2023	-27.62%
Rhythm Pharmaceuticals (RYTM)	March 2023	-26.77%

Mid-cap stocks are treated as having a market cap between $2B and $10B.