Pasqal Holding SA Ordinary Share (PSQL) had the lowest return in September 2026 by a small-cap US stock, returning -63.3%.

ASSET	MONTH	% RETURN
Pasqal Holding SA Ordinary Share (PSQL)	September 2026	-63.34%
Xanadu Quantum Technologies Limited Class B Subordinate Voting Shares (XNDU)	September 2026	-55.71%
AIFU (AIFU)	September 2026	-51.86%
Uniqure (QURE)	September 2026	-50.32%
Xtend AI Robotics (XTND)	September 2026	-50.21%
Polestar Automotive Holding UK PLC Class A ADS (PSNY)	September 2026	-47.51%
Claritev (CTEV)	September 2026	-46.31%
Ramaco Resources (METC)	September 2026	-41.14%
Ultragenyx (RARE)	September 2026	-40.39%
Scribe Therapeutics Inc Common Stock (SCTX)	September 2026	-39.93%
Alignment Healthcare LLC (ALHC)	September 2026	-39.33%
Sprinklr (CXM)	September 2026	-38.74%
Alight (ALIT)	September 2026	-37.01%
Loandepot (LDI)	September 2026	-36.45%
SL Science Holding Limited Ordinary Shares (SLBT)	September 2026	-36.33%
Cabaletta Bio (CABA)	September 2026	-36%
ITG, Inc Class A Common Stock (ITG)	September 2026	-35.81%
Oxford Industries (OXM)	September 2026	-35.51%
Elevra Lithium (ELVR)	September 2026	-34.8%
Goosehead Insurance (GSHD)	September 2026	-34.52%
Jade Biosciences (JBIO)	September 2026	-34.1%
Hemab Therapeutics Holdings, Inc Common Stock (COAG)	September 2026	-32.68%
Structure Therapeutics Inc American Depositary Shares (GPCR)	September 2026	-32.05%
Alkami Technology (ALKT)	September 2026	-31.96%
Standard Lithium (SLI)	September 2026	-31.46%

Small-cap stocks are treated as having a market cap between $300M and $2B.