First National (FXNC) had the lowest return between 1990 and 1999 by a US stock with a market cap of <= $250M, returning -100%.

ASSET	YEARS	% RETURN
First National (FXNC)	1990-1999	-100%
Cemtrex (CETX)	1990-1999	-100%
Gulf Resources (GURE)	1990-1999	-99.75%
Mega Matrix (MPU)	1990-1999	-99.5%
Coda Octopus (CODA)	1990-1999	-99.28%
Natural Health Trend (NHTC)	1990-1999	-98.81%
374Water Inc Common Stock (SCWO)	1990-1999	-98.58%
Evolution Petroleum (EPM)	1990-1999	-98.37%
Champions Oncology (CSBR)	1990-1999	-98.29%
Westwater Resources (WWR)	1990-1999	-97.85%
China Natural Resources (CHNR)	1990-1999	-97.69%
Odyssey Marine Exploration (OMEX)	1990-1999	-96.87%
Algorhythm (RIME)	1990-1999	-96.45%
New Concept Energy (GBR)	1990-1999	-96.21%
MEDIFAST (MED)	1990-1999	-95.83%
Reading International (RDI)	1990-1999	-92.4%
Good Times Restaurants (GTIM)	1990-1999	-92.23%
Emerson Radio (MSN)	1990-1999	-91.81%
Smith-Midland (SMID)	1990-1999	-89.02%
VirTra (VTSI)	1990-1999	-89%
Birks (BGI)	1990-1999	-88.83%
Tandy Leather Factory (TLF)	1990-1999	-88.4%
Soligenix (SNGX)	1990-1999	-86.8%
Protalix Biotherapeutics (PLX)	1990-1999	-86%
EDAP TMS (EDAP)	1990-1999	-85.14%