KULR Technology (KULR) had the highest return between 2000 and 2024 by a US stock, returning 7,099,900%.

ASSET	YEARS	% RETURN
KULR Technology (KULR)	2000-2024	7,099,900%
Mingteng International Corporation Inc Ordinary Shares (MTEN)	2000-2024	7,085,614.29%
Hirequest (HQI)	2000-2024	6,917,550%
Zivo Bioscience (ZIVO)	2000-2024	1,954,445.45%
QXO (QXO)	2000-2024	935,194.12%
DevvStream Corp Common Stock (DEVS)	2000-2024	751,900%
Sequans Communications (SQNS)	2000-2024	420,381.93%
GeoVax Labs (GOVX)	2000-2024	324,900%
DeFi Technologies (DEFT)	2000-2024	271,900%
MDxHealth SA ADR (MDXH)	2000-2024	263,233.33%
MKDWELL Tech Inc Ordinary Share (MKDW)	2000-2024	245,525%
Iqstel (IQST)	2000-2024	238,271.72%
Nutex Health (NUTX)	2000-2024	211,166.67%
Integra Resources (ITRG)	2000-2024	173,900%
NVIDIA (NVDA)	2000-2024	148,739.58%
Live Ventures (LIVE)	2000-2024	145,681.25%
Immatics (IMTX)	2000-2024	142,100%
Deckers Outdoor (DECK)	2000-2024	139,193.55%
Blackboxstocks (BLBX)	2000-2024	129,311.76%
Monster Beverage (MNST)	2000-2024	117,747.53%
Perspective Therapeutics (CATX)	2000-2024	106,233.33%
Axon Enterprise (AXON)	2000-2024	101,789.25%
Future Fintech (FTFT)	2000-2024	99,100%
Netflix (NFLX)	2000-2024	77,003.81%
BioNexus Gene Lab Corp Common stock (BGLC)	2000-2024	68,192.68%