BioNexus Gene Lab Corp Common stock (BGLC) had the highest return in 2021 by a US stock, returning 11,112,943.5%.

ASSET	YEAR	% RETURN
BioNexus Gene Lab Corp Common stock (BGLC)	2021	11,112,943.48%
ReShape Lifesciences (RSLS)	2021	10,933,156.47%
MDxHealth SA ADR (MDXH)	2021	865,354.55%
MicroCloud Hologram (HOLO)	2021	577,362.44%
Applied Digital (APLD)	2021	11,073.33%
Trump Media & Technology (DJTWW)	2021	2,299.56%
Destination XL (DXLG)	2021	2,067.94%
Zivo Bioscience (ZIVO)	2021	1,788.16%
Guardforce AI (GFAI)	2021	1,628%
Lightwave Logic (LWLG)	2021	1,500%
AMC Entertainment (AMC)	2021	1,136.37%
Arqit Quantum Inc Warrants (ARQQW)	2021	1,060%
LakeShore Biopharma (LSB)	2021	923.16%
Aehr Test Systems (AEHR)	2021	867.2%
Empire Petroleum (EP)	2021	814.42%
Atlas Lithium Corporation Common Stock (ATLX)	2021	700%
Greenwave Technology Solutions Inc Common Stock (GWAV)	2021	683.33%
GameStop (GME)	2021	681%
Cerberus Cyber Sentinel (CISO)	2021	584.21%
BriaCell Therapeutics (BCTXW)	2021	560.56%
Cassava Sciences (SAVA)	2021	538.89%
Obsidian Energy (OBE)	2021	514.93%
Mega Matrix (MPU)	2021	479.19%
Birks (BGI)	2021	464.02%
ZIM Integrated Shipping Services (ZIM)	2021	463.12%