Monster Beverage (MNST) had the highest return between 2001 and 2008 by a US stock in the S&P 500 (GSPC), returning 6,938.3%.

ASSET	YEARS	% RETURN
Monster Beverage (MNST)	2001-2008	6,938.29%
Tractor Supply (TSCO)	2001-2008	1,600.8%
Deckers Outdoor (DECK)	2001-2008	1,497.26%
Apple (AAPL)	2001-2008	1,047.68%
Hologic (HOLX)	2001-2008	895.81%
ANSYS (ANSS)	2001-2008	892.53%
Gilead Sciences (GILD)	2001-2008	879.91%
Old Dominion Freight Line (ODFL)	2001-2008	860.48%
Axon Enterprise (AXON)	2001-2008	805.19%
Booking (BKNG)	2001-2008	792.77%
Intuitive Surgical (ISRG)	2001-2008	681.5%
Altria (MO)	2001-2008	606.11%
Tyler Technologies (TYL)	2001-2008	560.97%
JB Hunt Transport Services (JBHT)	2001-2008	557.73%
Occidental Petroleum (OXY)	2001-2008	505.5%
Cognizant Technology Solutions Corp Class A (CTSH)	2001-2008	494.24%
Tapestry (TPR)	2001-2008	480.48%
CME (CME)	2001-2008	468.87%
Nucor (NUE)	2001-2008	465.96%
First Solar (FSLR)	2001-2008	463.1%
Texas Pacific Land Trust (TPL)	2001-2008	416.29%
Lennox International (LII)	2001-2008	397.13%
AutoZone (AZO)	2001-2008	393.7%
F5 Networks (FFIV)	2001-2008	384.45%
Arch Capital (ACGL)	2001-2008	371.24%