Sandisk (SNDK) has had the highest return between 2025 and 2026 by a large-cap US stock, returning 4,330.7%.

ASSET	YEARS	% RETURN
Sandisk (SNDK)	2025-2026	4,330.69%
Micron Technology (MU)	2025-2026	1,029.4%
Lumentum (LITE)	2025-2026	934.43%
Western Digital (WDC)	2025-2026	896.68%
Bloom Energy (BE)	2025-2026	865.26%
Seagate Technology (STX)	2025-2026	847.43%
Nebius (NBIS)	2025-2026	625.52%
Guardant Health (GH)	2025-2026	421.79%
AngloGold Ashanti (AU)	2025-2026	394.61%
Revolution Medicines (RVMD)	2025-2026	376.28%
TTM Technologies (TTMI)	2025-2026	362.59%
Millicom International Cellular (TIGO)	2025-2026	352.78%
Arrowhead Pharmaceuticals (ARWR)	2025-2026	350.74%
Intel (INTC)	2025-2026	345.13%
Enlight Renewable Energy Ltd Ordinary Shares (ENLT)	2025-2026	343.36%
Dell Technologies (DELL)	2025-2026	338.78%
Hecla Mining (HL)	2025-2026	316.63%
Ciena (CIEN)	2025-2026	316.32%
Lam Research (LRCX)	2025-2026	300.93%
Tower Semiconductor (TSEM)	2025-2026	297.71%
Grupo Cibest (CIB)	2025-2026	293.77%
ASE Industrial Holding Co Ltd ADR (ASX)	2025-2026	287.61%
IREN (IREN)	2025-2026	284.09%
IAMGold (IAG)	2025-2026	284.03%
First Majestic Silver (AG)	2025-2026	280.45%

Large-cap stocks are treated as having a market cap of $10B+.