QXO (QXO) had the highest return between 2011 and 2014 by a US stock with a market cap of $2B+, returning 7,392,225%.

ASSET	YEARS	% RETURN
QXO (QXO)	2011-2014	7,392,225%
Inventrust Properties (IVT)	2011-2014	1,067,615%
Vipshop (VIPS)	2011-2014	3,156.64%
ACADIA Pharmaceuticals (ACAD)	2011-2014	2,568.07%
Patrick Industries (PATK)	2011-2014	2,088.07%
Travere Therapeutics (TVTX)	2011-2014	1,260%
Regeneron Pharmaceuticals (REGN)	2011-2014	1,154.97%
Cheniere Energy (LNG)	2011-2014	1,152.66%
Alnylam Pharmaceuticals (ALNY)	2011-2014	878.81%
Acadia Healthcare (ACHC)	2011-2014	800.15%
Nexstar Broadcasting (NXST)	2011-2014	791.66%
Expedia (EXPE)	2011-2014	766.08%
Tesla (TSLA)	2011-2014	728.62%
Jazz Pharmaceuticals (JAZZ)	2011-2014	723.59%
Ambarella (AMBA)	2011-2014	655.89%
Domino's Pizza Inc Common Stock (DPZ)	2011-2014	548.61%
HCI (HCI)	2011-2014	529.27%
Lithia Motors (LAD)	2011-2014	525.87%
Ionis Pharmaceuticals (IONS)	2011-2014	505.29%
Ligand Pharmaceuticals (LGND)	2011-2014	493.19%
Silicon Motion Technology (SIMO)	2011-2014	491.22%
Addus HomeCare (ADUS)	2011-2014	479.24%
Axon Enterprise (AXON)	2011-2014	457.47%
American Airlines (AAL)	2011-2014	433.15%
Manhattan Associates (MANH)	2011-2014	429.52%