HCW Biologics (HCWB) had the highest return on May 20 by a nano-cap US stock, returning 133.7%.

ASSET	DATE	% RETURN
HCW Biologics (HCWB)	5/20/2026	133.65%
MetaVia (MTVA)	5/20/2026	46.7%
MicroAlgo (MLGO)	5/20/2026	41.42%
Matinas BioPharma (MTNB)	5/20/2026	31.85%
JBDI Holdings Limited Ordinary Shares (JBDI)	5/20/2026	31.1%
JIADE LIMITED Common stock (JDZG)	5/20/2026	30.29%
TNL Mediagene Ordinary Shares (TNMG)	5/20/2026	29.78%
Virax Biolabs Group Limited Ordinary Shares (VRAX)	5/20/2026	29.67%
CCSC Technology International Holdings Limited Ordinary Shares (CCTG)	5/20/2026	28.54%
Webus International Limited Ordinary Shares (WETO)	5/20/2026	25.75%
Concorde International Group Ltd Class A Ordinary Shares (CIGL)	5/20/2026	25.21%
Amesite Operating (AMST)	5/20/2026	24.54%
Pioneer Power Solutions (PPSI)	5/20/2026	23.41%
Integrated Media Technology (IMTE)	5/20/2026	20.7%
Regentis Biomaterials (RGNT)	5/20/2026	20.63%
Equus Total Return Closed Fund (EQS)	5/20/2026	19.74%
SMJ International (SMJF)	5/20/2026	19.51%
Netcapital (NCPL)	5/20/2026	19.47%
Bragg Gaming (BRAG)	5/20/2026	18.92%
Mereo BioPharma Group PLC ADR (MREO)	5/20/2026	18.91%
Freight Technologies (FRGT)	5/20/2026	18.69%
Autonomix Medical, Inc Common Stock (AMIX)	5/20/2026	18.66%
All In FutureTech Alliance (AIFA)	5/20/2026	18.38%
Accuray (ARAY)	5/20/2026	17.86%
Alzamend Neuro (ALZN)	5/20/2026	17.65%

Nano-cap stocks are treated as having a market cap of <= $50M.