Soligenix (SNGX) had the highest return between 1985 and 1990 by a US stock in the Nasdaq Composite (IXIC), returning 199,900%.

ASSET	YEARS	% RETURN
Soligenix (SNGX)	1985-1990	199,900%
Amgen (AMGN)	1985-1990	2,520.32%
Bridgford Foods (BRID)	1985-1990	1,793.94%
Crown Crafts (CRWS)	1985-1990	1,488.96%
RCM Technologies (RCMT)	1985-1990	1,400.48%
ClearOne (CLRO)	1985-1990	1,400%
Autodesk (ADSK)	1985-1990	1,156.93%
Telefonaktiebolaget LM Ericsson B ADR (ERIC)	1985-1990	1,139.63%
Microsoft (MSFT)	1985-1990	1,081.15%
Adobe Systems (ADBE)	1985-1990	1,005.48%
Newell Brands (NWL)	1985-1990	765.53%
CVB Financial (CVBF)	1985-1990	688.73%
Utah Medical Products (UTMD)	1985-1990	594.01%
Cracker Barrel Old Country Store (CBRL)	1985-1990	571.53%
PepsiCo (PEP)	1985-1990	521.5%
Natures Sunshine Products (NATR)	1985-1990	508%
Powell Industries (POWL)	1985-1990	507.16%
Washington Federal (WAFD)	1985-1990	429.36%
McGrath RentCorp (MGRC)	1985-1990	414.06%
Popular (BPOP)	1985-1990	407.63%
Superior Uniform (SGC)	1985-1990	396.52%
SLM (SLM)	1985-1990	380.04%
Paychex (PAYX)	1985-1990	367.97%
OraSure Technologies (OSUR)	1985-1990	354.38%
United Fire (UFCS)	1985-1990	350.4%