Brera Holdings PLC Class B Ordinary Shares (BREA) has had the highest return since October 1, 2021 by a US stock, returning 3,378,700%.

ASSET	% RETURN
Brera Holdings PLC Class B Ordinary Shares (BREA)	3,378,700%
Gogoro (GGR)	370,733.33%
Nvni Group Limited Ordinary Shares (NVNI)	307,900%
MDxHealth SA ADR (MDXH)	291,328.57%
DevvStream Corp Common Stock (DEVS)	233,900%
Synergy CHC Corp Common Stock (SNYR)	185,733.33%
Diversified Energy (DEC)	56,047.19%
CID HoldCo, Inc Warrants (DAICW)	33,650%
ZTST (ZTST)	30,631.89%
Wearable Devices (WLDSW)	19,815.25%
USA Rare Earth (USARW)	12,252.94%
Azitra (AZTR)	12,221.43%
HCM II Acquisition (HONDW)	7,661.9%
Castellum (CTM)	6,632.88%
Lottery (SEGG)	6,213.56%
Critical Metals Corp Warrants (CRMLW)	5,891.67%
Diginex Limited Ordinary Shares (DGNX)	4,581.69%
Nova Minerals Limited Warrant (NVAWW)	3,896%
QMMM Holdings Limited Ordinary Shares (QMMM)	3,880%
NewAmsterdam Pharma Company NV Warrant (NAMSW)	3,807.69%
Foremost Lithium Resource & Technology Ltd Common stock (FMST)	3,629.22%
Blue Gold Limited Warrant (BGLWW)	2,932%
Regencell Bioscience (RGC)	2,900.71%
TSS, Inc Common Stock (TSSI)	2,845%
Celestica (CLS)	2,626.17%