Ferguson (FERG) had the highest return between 2009 and 2010 by a large-cap US stock, returning 1,560,246.2%.

ASSET	YEARS	% RETURN
Ferguson (FERG)	2009-2010	1,560,246.15%
Teck Resources Ltd Class B (TECK)	2009-2010	1,162.83%
Jazz Pharmaceuticals (JAZZ)	2009-2010	952.41%
EXACT Sciences (EXAS)	2009-2010	949.12%
Tower Semiconductor (TSEM)	2009-2010	907.21%
Lululemon Athletica (LULU)	2009-2010	760.63%
Las Vegas Sands (LVS)	2009-2010	678.81%
Baidu (BIDU)	2009-2010	631.29%
Ford Motor (F)	2009-2010	630.01%
Cheniere Energy Partners (CQP)	2009-2010	616.23%
Wheaton Precious Metals (WPM)	2009-2010	510%
Netflix (NFLX)	2009-2010	495.21%
Somnigroup International (SGI)	2009-2010	480.56%
F5 Networks (FFIV)	2009-2010	469.63%
Tenet Healthcare (THC)	2009-2010	466.95%
Booking (BKNG)	2009-2010	437.97%
DexCom (DXCM)	2009-2010	394.57%
Freeport-McMoran Copper & Gold (FCX)	2009-2010	392.64%
AerCap (AER)	2009-2010	382.58%
Williams-Sonoma (WSM)	2009-2010	379.66%
CBRE Group Inc Class A (CBRE)	2009-2010	362.3%
Smurfit WestRock (SW)	2009-2010	356.01%
Incyte (INCY)	2009-2010	335.79%
Cummins (CMI)	2009-2010	323.71%
KKR (KKR)	2009-2010	318.03%

Large-cap stocks are treated as having a market cap of $10B+.