best performing mid cap stocks from 4/4/25 to 12/31/25

Regencell Bioscience (RGC) had the highest return between April 4, 2025 and December 31, 2025 by a mid-cap US stock, returning 3,218.1%.

ASSETDATE% RETURN
Regencell Bioscience (RGC)
4/4/2025 - 12/31/2025
3,218.06%
Abivax SA American Depositary Shares (ABVX)
4/4/2025 - 12/31/2025
2,334.21%
AXT (AXTI)
4/4/2025 - 12/31/2025
1,129.32%
Kodiak Sciences (KOD)
4/4/2025 - 12/31/2025
1,110.39%
Celcuity LLC (CELC)
4/4/2025 - 12/31/2025
1,062.47%
Ondas (ONDS)
4/4/2025 - 12/31/2025
1,009.09%
Praxis Precision Medicines  (PRAX)
4/4/2025 - 12/31/2025
810.25%
Tango Therapeutics (TNGX)
4/4/2025 - 12/31/2025
597.64%
Cogent Biosciences (COGT)
4/4/2025 - 12/31/2025
589.71%
Cipher Mining (CIFR)
4/4/2025 - 12/31/2025
556%
Planet Labs PBC (PL)
4/4/2025 - 12/31/2025
530.03%
Opendoor Technologies (OPEN)
4/4/2025 - 12/31/2025
525.54%
Arrowhead Pharmaceuticals (ARWR)
4/4/2025 - 12/31/2025
465.5%
nLIGHT (LASR)
4/4/2025 - 12/31/2025
459.85%
MBX Biosciences, Inc Common Stock (MBX)
4/4/2025 - 12/31/2025
397.48%
Navitas Semiconductor (NVTS)
4/4/2025 - 12/31/2025
363.64%
Applied Digital (APLD)
4/4/2025 - 12/31/2025
351.15%
Terawulf (WULF)
4/4/2025 - 12/31/2025
347.08%
Centrus Energy (LEU)
4/4/2025 - 12/31/2025
342.99%
Energy Fuels (UUUU)
4/4/2025 - 12/31/2025
311.9%
PACS (PACS)
4/4/2025 - 12/31/2025
305.81%
Indivior PLC Ordinary Shares (INDV)
4/4/2025 - 12/31/2025
293.85%
ViaSat (VSAT)
4/4/2025 - 12/31/2025
293.83%
Relay Therapeutics  (RLAY)
4/4/2025 - 12/31/2025
286.3%
Sibanye Gold Ltd ADR (SBSW)
4/4/2025 - 12/31/2025
283.07%
Mid-cap stocks are treated as having a market cap between $2B and $10B.