QXO (QXO) had the highest return between 2011 and 2013 by a US stock with a market cap of $2B+, returning 2,352,000%.

ASSET	YEARS	% RETURN
QXO (QXO)	2011-2013	2,352,000%
ACADIA Pharmaceuticals (ACAD)	2011-2013	2,000%
Patrick Industries (PATK)	2011-2013	1,339.31%
Vipshop (VIPS)	2011-2013	1,294.64%
Nexstar Broadcasting (NXST)	2011-2013	846.29%
Regeneron Pharmaceuticals (REGN)	2011-2013	741.97%
Travere Therapeutics (TVTX)	2011-2013	677.78%
Cheniere Energy (LNG)	2011-2013	667.25%
HCI (HCI)	2011-2013	658.21%
Expedia (EXPE)	2011-2013	601.04%
Acadia Healthcare (ACHC)	2011-2013	596.03%
Alnylam Pharmaceuticals (ALNY)	2011-2013	548.84%
Jazz Pharmaceuticals (JAZZ)	2011-2013	536.62%
Melco Resorts & Entertainment (MLCO)	2011-2013	497.87%
Ligand Pharmaceuticals (LGND)	2011-2013	486.4%
Tesla (TSLA)	2011-2013	460.44%
Addus HomeCare (ADUS)	2011-2013	435.8%
Generac (GNRC)	2011-2013	426.06%
Delek US Energy (DK)	2011-2013	409.09%
Ambarella (AMBA)	2011-2013	405.07%
Lithia Motors (LAD)	2011-2013	397.13%
Axos Financial (AX)	2011-2013	393.27%
Tyler Technologies (TYL)	2011-2013	387.73%
Domino's Pizza Inc Common Stock (DPZ)	2011-2013	373.73%
Mr Cooper (COOP)	2011-2013	347.62%