best performing mid-cap stocks apr 2025 to nov 2025

QMMM Holdings Limited Ordinary Shares (QMMM) had the highest return between April 1, 2025 and November 30, 2025 by a mid-cap US stock, returning 11,605.9%.

ASSETDATE% RETURN
QMMM Holdings Limited Ordinary Shares (QMMM)
4/1/2025 - 11/30/2025
11,605.88%
Abivax SA American Depositary Shares (ABVX)
4/1/2025 - 11/30/2025
1,894.09%
Regencell Bioscience (RGC)
4/1/2025 - 11/30/2025
1,243.51%
Cidara Therapeutics (CDTX)
4/1/2025 - 11/30/2025
927.96%
Terns Pharmaceuticals (TERN)
4/1/2025 - 11/30/2025
922.18%
Celcuity LLC (CELC)
4/1/2025 - 11/30/2025
915.46%
Cipher Mining (CIFR)
4/1/2025 - 11/30/2025
780.95%
Opendoor Technologies (OPEN)
4/1/2025 - 11/30/2025
662.38%
Olema Pharmaceuticals (OLMA)
4/1/2025 - 11/30/2025
661.29%
Ondas (ONDS)
4/1/2025 - 11/30/2025
586.96%
Cogent Biosciences (COGT)
4/1/2025 - 11/30/2025
569.22%
Terawulf (WULF)
4/1/2025 - 11/30/2025
472.32%
Praxis Precision Medicines  (PRAX)
4/1/2025 - 11/30/2025
419.74%
American Bitcoin (ABTC)
4/1/2025 - 11/30/2025
401.78%
Applied Digital (APLD)
4/1/2025 - 11/30/2025
382.21%
Sandisk (SNDK)
4/1/2025 - 11/30/2025
369.57%
Nuvation Bio (NUVB)
4/1/2025 - 11/30/2025
356.25%
GRAIL, LLC (GRAL)
4/1/2025 - 11/30/2025
336.5%
Arrowhead Pharmaceuticals (ARWR)
4/1/2025 - 11/30/2025
313.66%
Fluence Energy (FLNC)
4/1/2025 - 11/30/2025
305.79%
Eos Energy Enterprises (EOSE)
4/1/2025 - 11/30/2025
302.41%
Centrus Energy (LEU)
4/1/2025 - 11/30/2025
301.02%
TMC the metals (TMC)
4/1/2025 - 11/30/2025
288.83%
Energy Fuels (UUUU)
4/1/2025 - 11/30/2025
286.06%
Hut 8 Corp Common Stock (HUT)
4/1/2025 - 11/30/2025
279.11%
Mid-cap stocks are treated as having a market cap between $2B and $10B.