Rigetti Computing (RGTI) has had the highest return between 2023 and 2025 by a US stock in the Nasdaq Composite (IXIC) with a market cap of $10B+, returning 6,084%.

ASSET	YEARS	% RETURN
Rigetti Computing (RGTI)	2023-2025	6,084%
Applovin (APP)	2023-2025	5,444.03%
IREN (IREN)	2023-2025	4,535.11%
Palantir Technologies Inc Class A Common Stock (PLTR)	2023-2025	2,607.45%
MicroStrategy (MSTR)	2023-2025	1,889.91%
Rocket Lab USA (RKLB)	2023-2025	1,621.3%
Ast Spacemobile (ASTS)	2023-2025	1,614.37%
Robinhood Markets (HOOD)	2023-2025	1,472.76%
NVIDIA (NVDA)	2023-2025	1,134.8%
Sterling Construction (STRL)	2023-2025	972.64%
Credo Technology (CRDO)	2023-2025	955.18%
Fortress Transp & Infra Inv (FTAI)	2023-2025	941.15%
Coinbase Global (COIN)	2023-2025	820.86%
Insmed (INSM)	2023-2025	723.86%
Kratos Defense & Security Solutions (KTOS)	2023-2025	707.77%
BridgeBio Pharma (BBIO)	2023-2025	605.91%
Affirm (AFRM)	2023-2025	577.64%
Broadcom (AVGO)	2023-2025	545.44%
Flex (FLEX)	2023-2025	531.11%
Super Micro Computer (SMCI)	2023-2025	528.07%
Nebius (NBIS)	2023-2025	498.94%
Facebook (META)	2023-2025	487.31%
SoFi Technologies (SOFI)	2023-2025	470.75%
Symbotic (SYM)	2023-2025	464.88%
DoorDash, Inc Class A Common Stock (DASH)	2023-2025	426.33%