Advanced Micro Devices (AMD) had the highest return between 2016 and 2016 by a US stock in the S&P 500 (GSPC), returning 309.4%.

ASSET	YEARS	% RETURN
Advanced Micro Devices (AMD)	2016-2016	309.39%
NVIDIA (NVDA)	2016-2016	233.76%
ONEOK (OKE)	2016-2016	149.62%
Targa Resources (TRGP)	2016-2016	137.12%
Texas Pacific Land Trust (TPL)	2016-2016	136.02%
Steel Dynamics (STLD)	2016-2016	106.35%
Freeport-McMoran Copper & Gold (FCX)	2016-2016	99.85%
Newmont Goldcorp (NEM)	2016-2016	85.46%
Applied Materials (AMAT)	2016-2016	79.16%
Nordson (NDSN)	2016-2016	78.62%
Danaher (DHR)	2016-2016	76.98%
Quanta Services (PWR)	2016-2016	74.51%
Martin Marietta Materials (MLM)	2016-2016	66.09%
Cummins (CMI)	2016-2016	63.01%
Halliburton (HAL)	2016-2016	62.52%
IDEXX Laboratories (IDXX)	2016-2016	62.09%
Charter Communications (CHTR)	2016-2016	59.46%
Albemarle (ALB)	2016-2016	59.14%
Micron Technology (MU)	2016-2016	58.5%
Regions Financial (RF)	2016-2016	57.52%
Hewlett Packard Enterprise (HPE)	2016-2016	57.05%
Nucor (NUE)	2016-2016	54.72%
Diamondback Energy (FANG)	2016-2016	52.08%
F5 Networks (FFIV)	2016-2016	51.38%
EMCOR (EME)	2016-2016	50.63%