NVIDIA (NVDA) had the highest return between 2011 and 2017 by a US stock in the S&P 500 (GSPC), returning 1,245.1%.

ASSET	YEARS	% RETURN
NVIDIA (NVDA)	2011-2017	1,245.09%
Domino's Pizza Inc Common Stock (DPZ)	2011-2017	1,243.92%
Texas Pacific Land Trust (TPL)	2011-2017	1,184.96%
Expedia (EXPE)	2011-2017	1,146.61%
Tesla (TSLA)	2011-2017	1,059.98%
Regeneron Pharmaceuticals (REGN)	2011-2017	1,050.08%
Align Technology (ALGN)	2011-2017	1,025.01%
Builders FirstSource (BLDR)	2011-2017	989.5%
Constellation Brands Inc Class A (STZ)	2011-2017	959.55%
Broadcom (AVGO)	2011-2017	902.96%
Take-Two Interactive Software (TTWO)	2011-2017	791.07%
Charter Communications (CHTR)	2011-2017	759.67%
Tyler Technologies (TYL)	2011-2017	745.51%
Centene (CNC)	2011-2017	689.36%
EPAM Systems (EPAM)	2011-2017	681.31%
Netflix (NFLX)	2011-2017	667.84%
United Rentals (URI)	2011-2017	642.92%
Monolithic Power Systems (MPWR)	2011-2017	640.54%
Monster Beverage (MNST)	2011-2017	621.25%
Diamondback Energy (FANG)	2011-2017	608.47%
Huntington Ingalls Industries (HII)	2011-2017	599.92%
Smith AO (AOS)	2011-2017	595.76%
Mastercard (MA)	2011-2017	593.37%
Visa Inc Class A (V)	2011-2017	582.89%
UnitedHealth (UNH)	2011-2017	575.22%