NVIDIA (NVDA) has had the highest return between 2019 and 2025 by a US stock in the S&P 500 (GSPC), returning 5,650.2%.

ASSET	YEARS	% RETURN
NVIDIA (NVDA)	2019-2025	5,650.19%
Super Micro Computer (SMCI)	2019-2025	3,401.81%
Tesla (TSLA)	2019-2025	2,025.39%
Palantir Technologies Inc Class A Common Stock (PLTR)	2019-2025	1,746.3%
Broadcom (AVGO)	2019-2025	1,614.23%
Axon Enterprise (AXON)	2019-2025	1,611.91%
Howmet Aerospace (HWM)	2019-2025	1,485.05%
Quanta Services (PWR)	2019-2025	1,414.17%
KLA-Tencor (KLAC)	2019-2025	1,385.35%
Advanced Micro Devices (AMD)	2019-2025	1,304.33%
EMCOR (EME)	2019-2025	1,208.4%
Lam Research (LRCX)	2019-2025	1,144.18%
Arista Networks (ANET)	2019-2025	1,100.55%
Builders FirstSource (BLDR)	2019-2025	1,063.79%
Constellation Energy (CEG)	2019-2025	957.98%
Vistra Energy (VST)	2019-2025	944.79%
Monolithic Power Systems (MPWR)	2019-2025	901.98%
United Rentals (URI)	2019-2025	838.15%
Jabil Circuit (JBL)	2019-2025	810.54%
Fair Isaac (FICO)	2019-2025	805.19%
Applovin (APP)	2019-2025	785.71%
Williams-Sonoma (WSM)	2019-2025	784.76%
GE Aerospace (GE)	2019-2025	776.4%
Crowdstrike (CRWD)	2019-2025	730.43%
Cadence Design Systems (CDNS)	2019-2025	709.14%