Hirequest (HQI) had the highest return between 2001 and 2005 by a US stock, returning 43,752,250%.

ASSET	YEARS	% RETURN
Hirequest (HQI)	2001-2005	43,752,250%
InterContinental Hotels Group PLC ADR (IHG)	2001-2005	9,399,400%
Cemtrex (CETX)	2001-2005	6,791,020.23%
Perspective Therapeutics (CATX)	2001-2005	2,416,566.67%
Houston American Energy (HUSA)	2001-2005	815,339.5%
National Grid PLC ADR (NGG)	2001-2005	700,019.05%
Cryoport (CYRX)	2001-2005	71,251.35%
ImmunoPrecise Antibodies (HYFT)	2001-2005	64,185.71%
OPTIMIZERx (OPRX)	2001-2005	13,900%
NanoViricides (NNVC)	2001-2005	12,360%
Xcel Brands (XELB)	2001-2005	9,400%
First Majestic Silver (AG)	2001-2005	9,373.78%
Ziff Davis (ZD)	2001-2005	7,497.7%
TherapeuticsMD (TXMD)	2001-2005	7,400.01%
Dmc Global (BOOM)	2001-2005	5,578.48%
PetMed Express (PETS)	2001-2005	5,568.29%
Encore Capital (ECPG)	2001-2005	4,857.14%
CBAK Energy Technology (CBAT)	2001-2005	4,320%
USANA Health Sciences (USNA)	2001-2005	4,285%
Monster Beverage (MNST)	2001-2005	4,035.77%
MEDIFAST (MED)	2001-2005	3,628.01%
Broadwind Energy (BWEN)	2001-2005	3,260.13%
Cheniere Energy (LNG)	2001-2005	3,027.74%
Gulf Resources (GURE)	2001-2005	2,900%
DXP Enterprises (DXPE)	2001-2005	2,652%