best performing stocks past 4 years in the healthcare sector, in large stocks

Celestica (CLS) has had the highest return between December 23, 2021 and December 23, 2025 by a large-cap US stock or large-cap US stock, returning 2,702%.

ASSETDATE% RETURN
Celestica (CLS)
12/23/2021 - 12/23/2025
2,702.03%
Credo Technology (CRDO)
12/23/2021 - 12/23/2025
1,121.57%
Carpenter Technology (CRS)
12/23/2021 - 12/23/2025
1,115.56%
Palantir Technologies (PLTR)
12/23/2021 - 12/23/2025
929.87%
Ast Spacemobile (ASTS)
12/23/2021 - 12/23/2025
907.88%
Comfort Systems USA (FIX)
12/23/2021 - 12/23/2025
900.76%
Constellation Energy (CEG)
12/23/2021 - 12/23/2025
883.38%
YPF Sociedad Anonima (YPF)
12/23/2021 - 12/23/2025
825.52%
Oklo (OKLO)
12/23/2021 - 12/23/2025
738.93%
Fortress Transp & Infra Inv (FTAI)
12/23/2021 - 12/23/2025
725.08%
Vistra Energy (VST)
12/23/2021 - 12/23/2025
678.67%
Applovin (APP)
12/23/2021 - 12/23/2025
674.95%
TechnipFMC (FTI)
12/23/2021 - 12/23/2025
663.04%
Allegheny Technologies (ATI)
12/23/2021 - 12/23/2025
647.81%
Super Micro Computer (SMCI)
12/23/2021 - 12/23/2025
621.05%
Madrigal Pharmaceuticals (MDGL)
12/23/2021 - 12/23/2025
612.42%
Howmet Aerospace  (HWM)
12/23/2021 - 12/23/2025
598.12%
Vertiv (VRT)
12/23/2021 - 12/23/2025
591.45%
Summit Therapeutics (SMMT)
12/23/2021 - 12/23/2025
586.36%
Reddit (RDDT)
12/23/2021 - 12/23/2025
564.18%
Robinhood Markets (HOOD)
12/23/2021 - 12/23/2025
556.69%
Rocket Lab USA (RKLB)
12/23/2021 - 12/23/2025
542.1%
NVIDIA (NVDA)
12/23/2021 - 12/23/2025
537.12%
Insmed (INSM)
12/23/2021 - 12/23/2025
522.43%
Symbotic (SYM)
12/23/2021 - 12/23/2025
490.17%
Large-cap stocks are treated as having a market cap of $10B+.