best performing stocks past 4 years in the healthcare sector, in large stocks

Celestica (CLS) has had the highest return between October 12, 2021 and October 12, 2025 by a large-cap US stock or large-cap US stock, returning 2,498.3%.

ASSET DATE % RETURN
Celestica (CLS)
10/12/2021 - 10/12/2025
2,498.29%
Oklo (OKLO)
10/12/2021 - 10/12/2025
1,405.01%
Sterling Construction (STRL)
10/12/2021 - 10/12/2025
1,375.8%
Super Micro Computer (SMCI)
10/12/2021 - 10/12/2025
1,322.88%
Vistra Energy (VST)
10/12/2021 - 10/12/2025
1,116.5%
Credo Technology (CRDO)
10/12/2021 - 10/12/2025
1,047.36%
Comfort Systems USA (FIX)
10/12/2021 - 10/12/2025
964.78%
Constellation Energy (CEG)
10/12/2021 - 10/12/2025
901.71%
NVIDIA (NVDA)
10/12/2021 - 10/12/2025
781.11%
Fortress Transp & Infra Inv (FTAI)
10/12/2021 - 10/12/2025
737.35%
IONQ (IONQ)
10/12/2021 - 10/12/2025
712.07%
Ast Spacemobile (ASTS)
10/12/2021 - 10/12/2025
696.41%
Vertiv (VRT)
10/12/2021 - 10/12/2025
661.57%
Carpenter Technology (CRS)
10/12/2021 - 10/12/2025
650.98%
Palantir Technologies Inc Class A Common Stock (PLTR)
10/12/2021 - 10/12/2025
644.97%
Hims Hers Health (HIMS)
10/12/2021 - 10/12/2025
625.13%
Broadcom (AVGO)
10/12/2021 - 10/12/2025
609.89%
Flex (FLEX)
10/12/2021 - 10/12/2025
562.58%
Arista Networks (ANET)
10/12/2021 - 10/12/2025
551.48%
Symbotic (SYM)
10/12/2021 - 10/12/2025
548.96%
Applovin (APP)
10/12/2021 - 10/12/2025
541.05%
Howmet Aerospace  (HWM)
10/12/2021 - 10/12/2025
493.56%
Reddit (RDDT)
10/12/2021 - 10/12/2025
483.97%
EMCOR (EME)
10/12/2021 - 10/12/2025
477.23%
Astera Labs, Inc Common Stock (ALAB)
10/12/2021 - 10/12/2025
472.81%
Large-cap stocks are treated as having a market cap of $10B+.