Monster Beverage (MNST) had the highest return between 2000 and 2009 by a US stock in the S&P 500 (GSPC), returning 7,074.9%.

ASSET	YEARS	% RETURN
Monster Beverage (MNST)	2000-2009	7,074.89%
Deckers Outdoor (DECK)	2000-2009	3,775.93%
Intuitive Surgical (ISRG)	2000-2009	1,585.8%
NVR (NVR)	2000-2009	1,388.4%
BlackRock (BLK)	2000-2009	1,376.71%
Tapestry (TPR)	2000-2009	1,372.18%
Tractor Supply (TSCO)	2000-2009	1,218.5%
DaVita HealthCare Partners (DVA)	2000-2009	1,205.33%
Gilead Sciences (GILD)	2000-2009	1,111.97%
EOG Resources (EOG)	2000-2009	1,085.53%
Western Digital (WDC)	2000-2009	938.84%
Hologic (HOLX)	2000-2009	897.8%
Cognizant Technology Solutions Corp Class A (CTSH)	2000-2009	886.78%
Occidental Petroleum (OXY)	2000-2009	883.36%
JB Hunt Transport Services (JBHT)	2000-2009	875.82%
Old Dominion Freight Line (ODFL)	2000-2009	863.81%
CME (CME)	2000-2009	834.6%
Johnson Controls International (JCI)	2000-2009	830.15%
Contura Energy (CTRA)	2000-2009	754.46%
Quest Diagnostics (DGX)	2000-2009	719.68%
Laboratory Corporation of America (LH)	2000-2009	711.74%
Apple (AAPL)	2000-2009	703.76%
Henry Schein (HSIC)	2000-2009	654.78%
Axon Enterprise (AXON)	2000-2009	650.9%
CoreSite Realty (COR)	2000-2009	640.58%