BOXABL (BXBL) had the highest return on June 22 by a small-cap US stock, returning 44.7%.

ASSET	DATE	% RETURN
BOXABL (BXBL)	6/22/2026	44.7%
Nuvectis Pharma (NVCT)	6/22/2026	19.44%
Entera Bio (ENTX)	6/22/2026	19.35%
Faeth Therapeutics (FTH)	6/22/2026	17.36%
Mega Fortune Company Limited Ordinary Shares (MGRT)	6/22/2026	16.38%
Avalo Therapeutics (AVTX)	6/22/2026	14.94%
Kailera Therapeutics, Inc Common Stock (KLRA)	6/22/2026	13.72%
Cullinan Oncology LLC (CGEM)	6/22/2026	13.29%
Zura Bio Limited - Class A Ordinary shares (ZURA)	6/22/2026	11.61%
Damora Therapeutics (DMRA)	6/22/2026	11.04%
Generate Biomedicines, Inc Common Stock (GENB)	6/22/2026	11.04%
MoonLake Immunotherapeutics (MLTX)	6/22/2026	10.66%
Design Therapeutics (DSGN)	6/22/2026	10.13%
WhiteFiber, Inc Ordinary Shares (WYFI)	6/22/2026	10.09%
Liberty Latin America (LILA)	6/22/2026	9.77%
Polibeli Group Ltd Class A Ordinary Shares (PLBL)	6/22/2026	9.55%
Replimune (REPL)	6/22/2026	9.39%
Digital Turbine (APPS)	6/22/2026	9.21%
HIVE Digital Technologies (HIVE)	6/22/2026	9.13%
Candel Therapeutics (CADL)	6/22/2026	8.8%
T1 Energy (TE)	6/22/2026	8.79%
BUUU (BUUU)	6/22/2026	8.68%
Jade Biosciences (JBIO)	6/22/2026	8.66%
Silence Therapeutics (SLN)	6/22/2026	8.66%
Hemab Therapeutics Holdings, Inc Common Stock (COAG)	6/22/2026	8.51%

Small-cap stocks are treated as having a market cap between $300M and $2B.