Ovintiv (OVV) had the highest return in the 2000s by a US stock, returning 110,658,300%.

ASSET	DECADE	% RETURN
Ovintiv (OVV)	2000s	110,658,300%
QVC (QVCGA)	2000s	5,621,098.15%
Northern Oil & Gas (NOG)	2000s	3,882,411.54%
India Globalization Capital (IGC)	2000s	2,299,900%
Houston American Energy (HUSA)	2000s	1,598,586.28%
MAG Silver (MAG)	2000s	1,169,200%
National Grid PLC ADR (NGG)	2000s	1,161,476.47%
Know Labs (KNW)	2000s	1,068,548.85%
Perspective Therapeutics (CATX)	2000s	296,566.67%
Ring Energy (REI)	2000s	133,233.33%
Ocean Power Technologies (OPTT)	2000s	100,011.11%
Gulf Resources (GURE)	2000s	58,200%
Gyre Therapeutics (GYRE)	2000s	44,215.31%
Future Fintech (FTFT)	2000s	20,500%
TherapeuticsMD (TXMD)	2000s	19,503.88%
First Majestic Silver (AG)	2000s	17,191.56%
Companhia Siderurgica Nacional ADR (SID)	2000s	12,673.16%
NanoViricides (NNVC)	2000s	11,800%
Broadwind Energy (BWEN)	2000s	9,608.39%
MEDIFAST (MED)	2000s	8,793.12%
Monster Beverage (MNST)	2000s	7,074.89%
BRF SA ADR (BRFS)	2000s	5,806.86%
Clean Harbors (CLH)	2000s	4,790.88%
Amedisys (AMED)	2000s	4,612.96%
Banco Bradesco SA ADR (BBD)	2000s	4,247.1%