Capricor Therapeutics (CAPR) has had the highest return this month by a US stock with a market cap of $1B+, returning 402.6%.

ASSET	MONTH	% RETURN
Capricor Therapeutics (CAPR)	December 2025	402.62%
Anbio Biotechnology Class A Ordinary Shares (NNNN)	December 2025	75.11%
Alumis (ALMS)	December 2025	48.66%
Digitalbridge (DBRG)	December 2025	48.48%
Regencell Bioscience (RGC)	December 2025	41.09%
Nutex Health (NUTX)	December 2025	39.34%
Uipath (PATH)	December 2025	36.48%
Ast Spacemobile (ASTS)	December 2025	36.01%
Vera Therapeutics (VERA)	December 2025	34.55%
USA Rare Earth (USAR)	December 2025	28.89%
Eve (EVEX)	December 2025	28.31%
Praxis Precision Medicines (PRAX)	December 2025	28.2%
Critical Metals Corp Ordinary Shares (CRML)	December 2025	26.25%
Rubrik (RBRK)	December 2025	25.79%
Fluence Energy (FLNC)	December 2025	25.77%
MongoDB (MDB)	December 2025	25.48%
New Found Gold (NFGC)	December 2025	25%
Microchip Technology (MCHP)	December 2025	24.45%
CoreWeave, Inc Class A Common Stock (CRWV)	December 2025	23.93%
Borr Drilling (BORR)	December 2025	23.85%
MaxLinear (MXL)	December 2025	23.09%
D-Wave Quantum (QBTS)	December 2025	22.67%
Sana Biotechnology (SANA)	December 2025	22.14%
Samsara (IOT)	December 2025	21.76%
Intuitive Machines (LUNR)	December 2025	21.72%