Quhuo (QH) had the lowest return between 2021 and 2022 by a US stock, returning -99.8%.

ASSET	YEARS	% RETURN
Quhuo (QH)	2021-2022	-99.84%
Jiuzi (JZXN)	2021-2022	-99.75%
RYTHM (RYM)	2021-2022	-99.74%
Versus Systems Inc. (VS)	2021-2022	-99.74%
Ensysce Biosciences (ENSC)	2021-2022	-99.7%
BTC Digital (BTCT)	2021-2022	-99.68%
Entero Therapeutics (GRDX)	2021-2022	-99.68%
Entero Therapeutics (ENTO)	2021-2022	-99.68%
OceanPal (SVRN)	2021-2022	-99.65%
MetaVia (MTVA)	2021-2022	-99.54%
Akanda (AKAN)	2021-2022	-99.5%
Meiwu Technology (WNW)	2021-2022	-99.49%
Jianzhi Education Technology Group Company Limited American Depositary Shares (JZ)	2021-2022	-99.41%
Tantech (TANH)	2021-2022	-99.36%
Fangdd Network (DUO)	2021-2022	-99.33%
Sentage (SNTG)	2021-2022	-99.11%
American Bitcoin (ABTC)	2021-2022	-98.96%
Enveric Biosciences (ENVB)	2021-2022	-98.93%
Ucommune International (UK)	2021-2022	-98.85%
Motorsport Gaming Us LLC (MSGM)	2021-2022	-98.81%
Im Cannabis (IMCC)	2021-2022	-98.81%
Ebang International (EBON)	2021-2022	-98.74%
Micromobility (MCOM)	2021-2022	-98.73%
Quoin Pharmaceuticals Ltd DRC (QNRX)	2021-2022	-98.67%
Farmmi (FAMI)	2021-2022	-98.64%