Ovintiv (OVV) had the lowest return between 2010 and 2020 by a large-cap US stock, returning -88.7%.

ASSET	YEARS	% RETURN
Ovintiv (OVV)	2010-2020	-88.71%
YPF Sociedad Anonima (YPF)	2010-2020	-86.68%
Permian Resources (PR)	2010-2020	-85%
ArcelorMittal SA ADR (MT)	2010-2020	-81.75%
Deutsche Bank (DB)	2010-2020	-81.61%
Teva Pharma Industries Ltd ADR (TEVA)	2010-2020	-79.32%
Devon Energy (DVN)	2010-2020	-74.7%
BitMine Immersion Technologies (BMNR)	2010-2020	-72.5%
Petroleo Brasileiro Petrobras SA ADR (PBR)	2010-2020	-72.05%
Telefonica SA ADR (TEF)	2010-2020	-70.09%
Cenovus Energy (CVE)	2010-2020	-69.74%
Occidental Petroleum (OXY)	2010-2020	-67.63%
Petróleo Brasileiro SA - Petrobras (PBR.A)	2010-2020	-66.83%
Embraer SA ADR (ERJ)	2010-2020	-65.79%
TechnipFMC (FTI)	2010-2020	-64.8%
PG&E (PCG)	2010-2020	-62.67%
Banco Santander SA ADR (SAN)	2010-2020	-59.71%
Kinross Gold (KGC)	2010-2020	-59.61%
Allegheny Technologies (ATI)	2010-2020	-57.99%
Schlumberger (SLB)	2010-2020	-56.69%
Nokia (NOK)	2010-2020	-55.39%
Mosaic (MOS)	2010-2020	-54.74%
Summit Therapeutics (SMMT)	2010-2020	-52.53%
Banco Bilbao Viscaya Argentaria SA ADR (BBVA)	2010-2020	-51.61%
Tenaris SA ADR (TS)	2010-2020	-51.46%

Large-cap stocks are treated as having a market cap of $10B+.